|Posted by spotties admin on November 12, 2010 at 1:06 PM|
I have some good news to share with you! Dr. Rebecca Bellone and associates on the Appaloosa Project research team have just published the results of a study aimed at identifying SNPs (single nucleotide polymorphisms) associated with Appaloosa spotting (LP).
The results of this study can be viewed in this monthâ€™s special issue of Animal Genetics: Horse Genomics and the Dorothy Russell Havemeyer Foundation:
Animal Genetics article on recent LP research
â€œWe have identified three polymorphisms that are in perfect association with LP in several breeds of horses," says Bellone, chief molecular biologist for the Appaloosa Project. â€œWe will continue to work to determine the causative mutation, but in the meantime, these SNPs could be utilized to evaluate potential breeding animals.â€
Why is this so exciting? These SNPs can be used to DNA test horses for LP. Since this announcement has just been made, we do not yet know of any labs that will be offering the test. However, as I learn of these I will announce that information here.
Please note that the Appaloosa Project itself will not be offering DNA testing of this kind - we must remain focused on our research work, which is ongoing. However, we are hopeful that equine DNA testing facilities will soon offer this test!
As many of you know, having the option to test a young Appaloosa will revolutionize breeding. Many horses that have inherited the LP mutation donâ€™t display obvious coat patterning or â€œcharacteristicsâ€. Others donâ€™t have coat patterns that allow for easy classification of probable LP genotype by their appearance. With a DNA test for LP, breeders will no longer have to wait for horses to "colour", nor test breed in order to verify probable genotype.
Our sincere thanks to all the breeders who helped us by providing DNA samples during this study. Without your assistance, this achievement, and our final goal - the eventual identification of the LP mutation itself - would not be possible.
With much appreciation,